Clomid Increases Chances of Multiple Pregnancies

Coupe excited about pregnancy test results

Clomid and multiple pregnancies might mean a dream come true for you if you are experiencing infertility. Clomid is truly a miracle drug for many couples who are ready to become parents.

Clomid Information

Clomid, generically known as clomiphine citrate, is a fertility drug used to stimulate eggs that are developed and released from the ovaries. The drug is usually taken by mouth once a day for five days prior to ovulation. Clomid is only taken under a doctor's care after fertility tests are done to determine if the infertility a woman is experiencing is due to lack of ovulation. Clomid stimulates the ovaries to produce more egg follicles, which increase the chances of getting pregnant. Clomid may cause multiple pregnancies, such as twins or triplets, due to an increase in eggs being released.

Clomid Side Effects

Despite Clomid's popularity, it may cause side effects running from mild to serious. The doctor who prescribes Clomid for infertility should describe in detail the possible side effects. Mild side effects can be treated at home; more moderate to serious side effects should be reported to a doctor immediately.

Mild Side Effects

  • Flushing or feeling warm
  • Nauseous stomach
  • Throwing up
  • Breast pain
  • Headache
  • Spotting (vaginal bleeding)
  • Mood swings such as irritability and anxiety

Moderate to Serious Side Effects

  • Ovarian cysts
  • Blurred vision
  • Spotty vision
  • Double vision
  • Abdominal pain
  • Abdominal swelling
  • Weight gain
  • Shortness of breath


There are a couple of risks involved with taking Clomid. First, there is an increased risk of ovarian cancer with prolonged use. For this reason, most women will only be prescribed Clomid for six menstrual cycles, which seems to reduce the cancer risk according to studies. The second risk of taking Clomid is multiple pregnancies/births. Having twins may not seem like a risk to couples who are facing infertility, but multiple pregnancies, especially triplets and up, do pose a risk for mother and babies. Studies are being conducted such as the one done at the Advanced Fertility Center of Chicago to determine how much and when a woman should be given Clomid to control the amount of follicles released and thus control the relationship between Clomid and multiple pregnancies.

Clomid Benefits

Clomid is the least expensive and the least invasive fertility treatment available at this time. Clomid has a fairly high success rate and therefore remains a very popular fertility drug. Take a look at these success rate statistics from women who have used Clomid successfully:

  • Single births: 92 percent
  • Twins: 5 to 10 percent
  • Triplets: .5 percent

Clomid and Multiple Pregnancies

When taking Clomid, multiple pregnancy rates are significantly higher than natural multiple conception rates. In normally-conceived pregnancies, the percentage of women who conceive twins is 1.2 percent. In Clomid-conceived pregnancies, the percentage of women who conceive twins is 5 to 10 percent.

Other Reasons for Taking Clomid

Clomid is sometimes prescribed to treat other problems, including male infertility. Here are the details:

  • Male infertility: Clomid may help men who have a low sperm count or poor motility since Clomid stimulates the glands to produce heartier sperm. Clomid is not responsible for multiple births when men are taking it.
  • Fibrocystic Breasts: Clomid improves breast conditions.
  • Breast Milk Production: stops breast from producing milk.

What's Next After Clomid?

If you do not become pregnant after using clomid for six months, there are other options that you can discuss with your fertility doctor. The following two options may be suggested by your doctor:

  • FSH (Follicle stimulating hormone) given by injection, which is stronger than Clomid.
  • IVF: Inv itro-fertilization.
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Clomid Increases Chances of Multiple Pregnancies