Side Effects of Using Clomid

Research Clomid facts.

Many women find that the side effects of using Clomid are not bothersome enough to stop taking the fertility medication. Others have serious reactions to the drug. Each person is unique and a wide range of reactions to Clomid exist.

What are the Side Effects of Using Clomid?

Women's reactions to Clomid vary significantly, with some experiencing practically no side effects and others experiencing serious reactions. While exploring options in infertility treatment, many women find Clomid to be a very effective solution. The short-term drug is used up to six months before moving on to another treatment for infertility if Clomid is unsuccessful.

Common Clomid Side Effects

The good news is that most women do not experience significant side effects while taking the medication. Common side effects of using Clomid include physical and emotional changes.

  • Abdominal cramps, pain, or bloating
  • Enlarged ovaries
  • Headaches or migraines
  • Heavy periods
  • Hot flashes
  • Mood swings
  • Nausea
  • Tender breasts
  • Uterine bleeding or spotting between periods

Keep in mind that many women experience no side effects while taking Clomid and some factors may play into reactions. For example, women who are prone to headaches or migraines may have a higher incidence of headaches and migraines while taking the fertility medication.

Rare Side Effects

Some Clomid side effects occur in rare instances, but they should be considered a possibility if you plan to take the medication. More research is necessary to determine whether the rare side effects are caused by Clomid or other factors. Women have, in rare case, reported:

  • Constipation or diarrhea
  • Depressed mood
  • Dizzy or lightheaded
  • Dry hair
  • Excessive appetite
  • Excessive urination
  • Fatigue
  • Hair loss
  • Insomnia
  • Nervousness
  • Rashes
  • Vaginal dryness
  • Vertigo
  • Weight loss or weight gain

Serious Side Effects

Rare side effects include serious problems that require immediate medical attention. Women experiencing any of the following conditions while taking Clomid should contact their physicians right away.

  • Allergic skin reactions, which may include hives, itchiness, rashes, swelling.
  • Breathing problems associated with allergic reactions, including wheezing, difficulty swallowing, and trouble breathing.
  • Vision problems, such as double vision, blurred sight, light flashes, and light sensitivity.
  • Severe abdominal pain, which should be reported to your doctor right away.

Ovarian Hyperstimulation Syndrome

Ovarian hyperstimulation syndrome (OHSS) may be a side effect in some women taking Clomid. OHSS is a serious condition that causes the ovaries to enlarge and can cause the ovaries to rupture in severe cases. Women taking the medication should contact their doctors if they have the following symptoms:

  • Severe abdominal pain
  • Vomiting or extreme nausea
  • Stomach enlargement
  • Significant weight gain
  • Diarrhea

Clomid and Birth Defects

Clomid is a Category X medication in the Food and Drug Administration's classification. This means that the drug can cause birth defects. Considering that the medication is used to treat infertility, it isn't likely that a pregnant woman would take Clomid.

A possible link between fertility drugs and autism may make some women concerned about using Clomid. A 2010 Harvard University study found that women who took fertility drugs long term were more likely to have a child with autism. However, the study is quite new and many experts believe that risks are minimal. Women who have a history of autism in their families should discuss concerns about fertility drugs and autism.

Before Taking Clomid

Before taking Clomid it is important to have an evaluation to determine if liver function and estrogen levels are normal. Those interested in taking the fertility medication should discuss the possible side effects with their doctors.

Side Effects of Using Clomid